Bipolar Disorder
Posted on June 9th, 2012

Dr. Nishan Wijesinha (Chairman) – Training and Restoration House for Bipolar Disorder

Bipolar disorder or bipolar affective disorder, historically known as manic-depressive disorder, is a psychiatric diagnosis that describes a category of mood disorders defined by the presence of one or more episodes of abnormally elevated energy levels, cognition, and mood with or without one or more depressive episodes. The elevated moods are clinically referred to as mania or, if milder, hypomania. It is a devastating long-lasting disorder leading to total mental instability, suicide and self harm, if not treated with Amino butyric acid.

Gamma-aminobutyric acid (GABA) which is a non-essential amino acid formed from glutamic acid with the help of vitamin B6. GABA (gamma-aminobutyric acid) is found in almost every region of brain, and is formed through the activity of the enzyme glutamic acid decarboxylase (GAD). GAD catalyzes the formation of GABA from glutamic acid. GAD requires vitamin B6 (pyridoxal phosphate) as a cofactor, which can be used to regulate the levels of GABA. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system to block the transmission of an impulse from one cell to another in the central nervous system.. In humans, GABA acts at inhibitory synapses in the brain and spinal cord.

Gamma-aminobutyric acid functions as a neurotransmitter in the central nervous system, decreasing neuron activity thus preventing them from over firing with Niacinamide(B3) and Inositol.

GABA prevents anxiety and stress-related messages from reaching the motor centers of the brain, and is essential for brain metabolism.

GABA has been used in the treatment of depression, manic-depressive (bipolar) disorder, seizures, premenstrual dysphoric (feeling depressed) disorder, and anxiety. GABA serves as a inhibitory neurotransmitter to block the transmission of an impulse from one cell to another in the central nervous system. GABA improves sleep cycles leading to more restful sleeping. GABA has powerful stabilizing effects on blood pressure. GABA is a very effective analgesic, eliminating pain from chronic conditions such as arthritis and lower back pain.

So called alternate treatments such as the commonly used Sodium valproate has the highest risk of birth defects, seizures, increased tremors, sedation, hair loss, shrinking of skin and total numbness, which also pose grave risk to mother and child; which in total should not be administered at all as it is a cheap alternate for GABA.

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