Hyperglycemia and Hypoglycemia in diabetic
Posted on May 1st, 2018

Dr Hector Perera            London

As we know there are two types of diabetics, type 1 and type 2. Some people are totally unaware if they suffer from diabetics because they haven’t consulted a doctor for their conditions. In England there are millions of people who are unaware if they suffer from diabetic. After a certain age it is important to check if they have diabetic for your own safety.

Hyperglycemia is the medical term for high blood sugar, which arises due to the body’s inability to remove glucose from the blood so that cells can use it for energy. The condition usually only affects people with diabetes because these individuals have problems with insulin – the hormone required for glucose uptake.


Hyperglycemia symptoms tend to develop over the course of several weeks and may include the following. Dry mouth and increased thirst leading to frequent intake of water. This is referred to as polydipsia. Increased urination, particularly at night, which is referred to as polyuria. Increased hunger and food intake, which is referred to as polyphagia and fatigue. Further symptoms that may eventually develop include blurred vision, weight loss, nerve damage, kidney problems and heart problems. Some people totally ignore these things but they are not bothered to check if something is wrong with them.


People who have diabetes are unable to break glucose down into energy due either to an inadequate level of insulin or insulin failing to work properly. This means glucose remains in the blood causing a high blood sugar level. Diabetes occurs in two forms, type 1 diabetes and type 2 diabetes.

Hyperglycemia is the scientific term for high blood glucose levels Hyperglycemia occurs when people with diabetes have too much sugar in their bloodstream.

Hyperglycemia should not be confused with hypoglycemia, which is when blood sugar levels go too low. You should aim to avoid spending long periods of time with high blood glucose levels.

What is hyperglycemia?

Hyperglycemia, the term for expressing high blood sugar, has been defined by the World Health Organisation as, blood glucose levels greater than 7.0 mmol/L (126 mg/dl) when fasting. Blood glucose levels greater than 11.0 mmol/L (200 mg/dl) 2 hours after meals.

Although blood sugar levels exceeding 7 mmol/L for extended periods of time can start to cause damage to internal organs, symptoms may not develop until blood glucose levels exceed 11 mmol/L.

More immediate reasons for hyperglycemia include, missing a dose of diabetic medication, tablets or insulin. Eating more carbohydrates than your body and/or medication can manage. Being mentally or emotionally stressed (injury, surgery or anxiety) .Contracting an infection.

Is hyperglycemia serious?

Hyperglycemia can be serious if, blood glucose levels stay high for extended periods of time – this can lead to the development of long term complications. Blood glucose levels rise dangerously high – this can lead to short term complications.

In the short term.

Short term complications of very high blood sugar levels include ketoacidsosis and hyperosmolar hyperglycemic nonketotic syndrome.

Ketoacidosis is a dangerous complication that mainly affects people with type 1 diabetes but can also affect some people with type 2 diabetes that are dependent on insulin. The risk of ketoacidosis becomes significant if blood glucose levels rise above 15 mmol/l (270 mg/dl).

How to avoid and deal with hyperglycemia?

Minimising long time exposure to high blood sugar levels is one of the key objectives of diabetes control.

Testing blood sugar levels will help in managing hyperglycemia. People who take insulin may be able to take additional insulin. However, only take additional insulin if your doctor is happy for you to do so, as miscalculations could lead to dangerously low blood sugar levels. Before you increase the amount of insulin injection, you must consult the doctor about it.

Diabetes UK advise people with type 1 diabetes to test for ketones if blood glucose levels rise above 15 mmol/l or the signs of ketoacidosis appear. Contact your health team if high levels of ketones are present.

Diabetic coma

A diabetic coma is a life-threatening diabetes complication that causes unconsciousness. If you have diabetes, dangerously high blood sugar (hyperglycemia) or dangerously low blood sugar (hypoglycemia) can lead to a diabetic coma.

If you lapse into a diabetic coma, you’re alive — but you can’t awaken or respond purposefully to sights, sounds or other types of stimulation. Left untreated, a diabetic coma can be fatal.

The prospect of a diabetic coma is scary, but fortunately you can take steps to help prevent it. Start by following your diabetes treatment plan.


Before developing a diabetic coma, you’ll usually experience signs and symptoms of high blood sugar or low blood sugar.

High blood sugar (hyperglycemia)

If your blood sugar level is too high, you may experience:

Increased thirst, frequent urination, Fatigue, Nausea and vomiting, Shortness of breath, Stomach pain, Fruity breath odours, a very dry mouth, a rapid heartbeat.

Low blood sugar (hypoglycemia)

Signs and symptoms of a low blood sugar level may include:

Shakiness or nervousness, anxiety, fatigue, weakness, sweating, hunger, nausea, dizziness or light-headedness and difficulty speaking. One might not get all these conditions but these are the signs to watch out.


Some people, especially those who’ve had diabetes for a long time, develop a condition known as hypoglycemia unawareness and won’t have the warning signs that signal a drop in blood sugar.

If you experience any symptoms of high or low blood sugar, test your blood sugar and follow your diabetes treatment plan based on the test results. If you don’t start to feel better quickly, or you start to feel worse, call for emergency help.

When to see a doctor

A diabetic coma is a medical emergency. If you feel extreme high or low blood sugar signs or symptoms and think you might pass out, call 911 or your local emergency number. Your comments are welcomed perera6@hotmail.co.uk

One Response to “Hyperglycemia and Hypoglycemia in diabetic”

  1. Ananda-USA Says:

    Papaya Leaf Holds a Cure for Dengue Fever

    Thu, May 3, 2018

    May 03 (TN) A traditional herbal remedy for the dangerous tropical disease ‘dengue fever’ could be turned into a pill to treat patients thanks to groundbreaking research by scientists at the University of Nottingham’s Malaysia Campus (UNMC).

    Papaya leaf juice has for a long time been used in some areas of India and South East Asia as a treatment for dengue fever. A compound in the juice is known to help with blood clotting and can restrict the internal bleeding caused by the disease.

    Now, thanks to funding from the Malaysian Ministry of Higher Education, a team of chemical engineers in the University’s Food and Pharmaceutical Engineering Group in Malaysia are tackling the challenge of extracting the bioactive compound ‘carpaine’ for use in a pill for dengue.

    Dengue is a mosquito-born viral infection found in tropical and sub-tropical climates and tends to be concentrated in urban and semi-urban areas. The infection causes flu-like symptoms and can develop into a potentially fatal form of the disease – Dengue Haemorrhagic Fever. The incidence worldwide has grown dramatically in recent decades with severe dengue now a leading cause of hospitalisation and death among children and adults in Asia and Latin America. There is currently no vaccine for it.

    Leading the research at UNMC, Associate Professor Dr Ching Lik Hii, said: “Dengue has been a big issue in Malaysia and other countries with similar climates for more than 20 years. People are dying and more people are being infected as the Aedes mosquito population grows and becomes more active. This global problem inspired me to look for something that is a well-known traditional plant based remedy and make it much easier to process and consume”.

    “We are targeting the active bio-compound carpaine which we know can increase blood platelets and therefore helps reduce internal bleeding. We are also looking at whether the younger leaves or the older leaves contain more carpaine, and also whether the stems of the papaya plant could also be useful.”

    The carpaine compound is extracted by using alcohol. An acid-base extraction procedure is then used to yield crude carpaine material. Further purification steps produces solid carpaine that is at least 95% pure. At the end of the three-year project, the team hopes to have developed the best processing method to achieve the highest yield of carpaine. Other aims are to find out how the carpaine degrades during storage and which parts of the papaya plant are best to use.

    The challenge will eventually be to find adequate supply sources of papaya leaf because there are not many large papaya farms in Malaysia and existing farms do not harvest the leaves as their priority is to grow papaya fruit.

    Eventually the researchers aim to work with industry partners in Malaysia and beyond to produce a carpaine medication. They anticipate the product could take at least ten years to bring to market because extensive approvals and clinical trials are needed.

    Read More:: TN (Source)

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